Manchester City, who finished eight points adrift of the Blues, travel to West Brom while Manchester United face Tottenham at Old Trafford.
Arsenal host West Ham, Liverpool go to Stoke, Newcastle play Southampton and Leicester welcome Sunderland.
Promoted trio Bournemouth, Watford and Norwich face Aston Villa, Everton and Crystal Palace respectively.
The top-flight season starts a week earlier than last season - on the same weekend as the Football League - as the 2016 European Championship starts on 10 June.
Click here for the Premier League fixtures in full.
In the Championship, relegated Hull host Huddersfield, Burnley travel to Leeds and Queens Park Rangers are at Charlton.